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KMID : 0361020240670010022
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Korean Journal of Otolaryngology - Head and Neck Surgery
2024 Volume.67 No. 1 p.22 ~ p.27
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The Efficacy of Fibrin Sealant to Reduce Complications After Rhinoplasty: A Meta-Analysis
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Kang Jeong-Wook
Bang Je-He
Son Seung-Yup
Lee Kun-Hee
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Abstract
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Background and Objectives Fibrin sealant (FS) is widely used to reduce postoperativebleeding. This analysis aimed to assess the efficacy of FS to reduce complications after rhino-pl a s t y.
Materials and Method We searched PubMed, Scopus, Embase, the Cochrane Library, andthe Web of Science database for articles on FS and rhinoplasty from the inception of publica-tion to December 29, 2021. Post-rhinoplasty complications, such as edema and ecchymosis,were recorded. The final meta-analysis was performed using three studies.
Results Two subgroups were created based on the FS usage after rhinoplasty. The FS effecton edema reduction was favorable on the postoperative day-1 (standardized mean difference[SM D]=-1.07 [-1.70; -0.45]). In addition, the FS effect on ecchymosis reduction was favorableon the postoperative day-1 postoperative (SMD=-1.33 [-2.15; - 0.50]).
Conclusion Our study shows that FS reduces the early complications of rhinoplasty.
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KEYWORD
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Adverse effect, Blood coagulation, Ecchymosis, Fibrin, Meta-analysis, Rhinoplasty
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